In this Supermicro Open Storage Summit 2025 segment, theCUBE’s Rob Strechay hosts Junxia Zhou (Supermicro), Shiva Gurumurthy (AMD), Sagy Volkov (Lightbits) and Simon Lightstone (EDB) to explore how enterprises are modernizing applications for the AI era. The panel dives into the convergence of AI inference and OLTP workloads, the role of Postgres as a modern data backbone, and how high-performance block storage and Kubernetes orchestration are shaping next-generation application platforms. Junxia Zhou outlines how Supermicro’s rack-scale, plug-and-play solutions simplify deployment, improve energy efficiency and accelerate time-to-production for AI infrastructure. Shiva Gurumurthy highlights AMD’s broad AI portfolio, from EPYC CPUs and Instinct GPUs to Versal FPGAs and Pensando DPUs, demonstrating industry-leading performance-per-watt and significant cost savings at scale. Sagy Volkov details Lightbits’ software-defined storage innovations, including NVMe over TCP and intelligent flash management, delivering millions of IOPS with minimal footprint for Kubernetes and multi-cloud environments. Simon Lightstone shares how EDB is advancing Postgres for mission-critical workloads with simplified high availability, sovereign AI data factories and a tightly integrated partnership with Supermicro. The discussion underscores why enterprises must shift beyond legacy systems toward open, cloud-native architectures. By aligning compute, storage and data platforms across trusted partners, organizations can build flexible AI factories that reduce total cost of ownership while preparing for mission-critical AI applications.